Effect of Medium pH on Antibiotic Activity against Syrian Brucella spp. Isolates

effect of medium ph on antibiotic activity against syrian brucella spp. isolates

background: brucellosis is an endemic zoonosis in syria, affecting large numbers of animals. there are an increasing number of cases in humans. brucella is a facultative intracellular pathogen, a small, non-motile, gram-negative coccobacillus, which causes abortion in domestic animals and a febrile illness in humans. methods: one hundred isolates collected from different syrian regions were con...

Efficacy evaluation of some antibiotics against syrian brucella spp isolates, in vitro

Brucellosis is an endemic zoonosis in Syria, affecting large numbers of animals and there are an increasing number of cases in humans. The aim of this study is to investigate the in vitro efficacy of various traditional and new antibiotics against 89 Brucella isolates (isolated from domestic animals) collected from different Syrian regions. Minimum inhibitory concentrations (MICs) of seventeen ...

Effect of pH on the activity of erythromycin against 500 isolates of gram-negative bacilli.

Erythromycin was found to be a more effective inhibitor of gram-negative bacilli in alkaline medium than in neutral or acid medium. A definite effect was noted with all of 500 recent clinical isolates of Escherichia coli, Klebsiella-Enterobacter, Pseudomonas aeruginosa, and Proteus mirabilis studied, but it was most striking with E. coli. At pH 8.5 all strains, except for 14% of those of P. mir...

In Vitro Activity of Tigecycline Against Brucella spp. Tigesiklinin Brucella spp‘ye Karşı İn Vitro Aktivitesi

Effect of inoculum, pH, and medium on the activity of ciprofloxacin against anaerobic bacteria.

The in vitro activity of ciprofloxacin against 30 Bacteroides fragilis group, 30 Clostridium, and 30 Peptococcaceae strains was determined by the agar dilution method in two different culture media at three pH and in three inoculum densities. In Wilkins-Chalgren agar the MICs for 90% of the strains were 0.12 micrograms/ml for B. fragilis, 0.5 micrograms/ml for Clostridium spp., and 2 micrograms...